Small kernel 501 (smk501) encodes the RUBylation activating enzyme E1 subunit ECR1 (E1 C-TERMINAL RELATED 1) and is essential for multiple aspects of cellular events during kernel development in maize.
作者： Junjie Fu , Xuemei Du , Jianhua Wang , Riliang Gu , Li Li
DOI: 10.1111/NPH.17354
关键词:
摘要: RUBylation plays essential roles in plant growth and development through regulating Cullin-RING ubiquitin E3 ligase (CRL) activities the CRL-mediated protein degradations. However, function of kernel remains unclear. Through genetic molecular analyses a small 501 (smk501) mutant maize (Zea mays L.), we cloned smk501 gene, revealed its function, defined pathway seed development. Smk501 encodes activating enzyme E1 subunit ZmECR1 (E1 C-TERMINAL RELATED 1) protein. Destruction by mutation resulted less embryo endosperm cell number smaller size. The transcriptome proteome profiling, hormone evaluation proliferation observation that disturbing expression mainly affects pathways on signal transduction, cycle progression starch accumulation during In addition, zmaxr1 (Auxin resistant 1), another RUB subunit, also showed similar defects Double zmecr1 lead to empty pericarp phenotype. is novel regulatory affecting development, majorly functions modifying multiple cellular progresses.
sci-hub.st 参考文章(75)
A L Haas, P Ahrens, P M Bright, H Ankel, Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. Journal of Biological Chemistry. ,vol. 262, pp. 11315- 11323 ,(1987) , 10.1016/S0021-9258(18)60961-5
Eduardo Bueso, Lesia Rodriguez, Laura Lorenzo-Orts, Miguel Gonzalez-Guzman, Enric Sayas, Jesús Muñoz-Bertomeu, Carla Ibañez, Ramón Serrano, Pedro L. Rodriguez, The single-subunit RING-type E3 ubiquitin ligase RSL1 targets PYL4 and PYR1 ABA receptors in plasma membrane to modulate abscisic acid signaling Plant Journal. ,vol. 80, pp. 1057- 1071 ,(2014) , 10.1111/TPJ.12708
R. Schmidt, F. Burr, B Burr, Transposon tagging and molecular analysis of the maize regulatory locus opaque-2. Science. ,vol. 238, pp. 960- 963 ,(1987) , 10.1126/SCIENCE.2823388
Xian-Jun Song, Wei Huang, Min Shi, Mei-Zhen Zhu, Hong-Xuan Lin, A QTL for rice grain width and weight encodes a previously unknown RING-type E3 ubiquitin ligase Nature Genetics. ,vol. 39, pp. 623- 630 ,(2007) , 10.1038/NG2014
F. Brioudes, A.-M. Thierry, P. Chambrier, B. Mollereau, M. Bendahmane, Translationally controlled tumor protein is a conserved mitotic growth integrator in animals and plants. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 16384- 16389 ,(2010) , 10.1073/PNAS.1007926107
Jayashree Mitra, Greg H Enders, Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells. Oncogene. ,vol. 23, pp. 3361- 3367 ,(2004) , 10.1038/SJ.ONC.1207446
Sunethra Dharmasiri, Nihal Dharmasiri, Hanjo Hellmann, Mark Estelle, The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. The EMBO Journal. ,vol. 22, pp. 1762- 1770 ,(2003) , 10.1093/EMBOJ/CDG190
S. Lim, P. Kaldis, Cdks, cyclins and CKIs: roles beyond cell cycle regulation Development. ,vol. 140, pp. 3079- 3093 ,(2013) , 10.1242/DEV.091744
Matthew D. Petroski, Raymond J. Deshaies, Function and regulation of cullin-RING ubiquitin ligases. Nature Reviews Molecular Cell Biology. ,vol. 6, pp. 9- 20 ,(2005) , 10.1038/NRM1547
Richard D. Vierstra, The ubiquitin–26S proteasome system at the nexus of plant biology Nature Reviews Molecular Cell Biology. ,vol. 10, pp. 385- 397 ,(2009) , 10.1038/NRM2688