Heterochromatinization associated with cell differentiation as a model to study DNA double strand break induction and repair in the context of higher-order chromatin structure.
作者： Martin Falk , Emilie Lukášová , Lenka Štefančíková , Elena Baranová , Iva Falková
DOI: 10.1016/J.APRADISO.2013.01.029
关键词:
摘要: … We show that immature granulocytes form γH2AX and 53BP1 foci, contrary to the mature cells; … Even though, γH2AX foci “move” out of the dense chromatin. ► 53BP1 enters HP1β …
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researchgate.net 参考文章(67)
Marion Cremer, Johann von Hase, Tanja Volm, Alessandro Brero, Gregor Kreth, Joachim Walter, Christine Fischer, Irina Solovei, Christoph Cremer, Thomas Cremer, Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Research. ,vol. 9, pp. 541- 567 ,(2001) , 10.1023/A:1012495201697
Larry M. Wahl, Sharon M. Wahl, Lesley E. Smythies, Phillip D. Smith, Isolation of Human Monocyte Populations Current protocols in immunology. ,vol. 70, ,(2005) , 10.1002/0471142735.IM0706AS70
Marina N Nikiforova, James R Stringer, Ruthann Blough, Mario Medvedovic, James A Fagin, Yuri E Nikiforov, Proximity of Chromosomal Loci That Participate in Radiation-Induced Rearrangements in Human Cells Science. ,vol. 290, pp. 138- 141 ,(2000) , 10.1126/SCIENCE.290.5489.138
Aline Meulle, Bernard Salles, Danièle Daviaud, Philippe Valet, Catherine Muller, Positive Regulation of DNA Double Strand Break Repair Activity during Differentiation of Long Life Span Cells: The Example of Adipogenesis PLoS ONE. ,vol. 3, pp. e3345- ,(2008) , 10.1371/JOURNAL.PONE.0003345
JOHN H. FRENSTER, Ultrastructural Continuity between Active and Repressed Chromatin Nature. ,vol. 205, pp. 1341- 1342 ,(1965) , 10.1038/2051341A0
Emilie Lukášová, Zdeněk Kořistek, Martin Falk, Stanislav Kozubek, Sergei Grigoryev, Michal Kozubek, Vladan Ondřej, Iva Kroupová, Methylation of histones in myeloid leukemias as a potential marker of granulocyte abnormalities Journal of Leukocyte Biology. ,vol. 77, pp. 100- 111 ,(2005) , 10.1189/JLB.0704388
Aaron A Goodarzi, Penny A Jeggo, 'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite. F1000 Medicine Reports. ,vol. 1, pp. 21- 21 ,(2009) , 10.3410/B1-21
H. Scherthan, L. Hieber, H. Braselmann, V. Meineke, H. Zitzelsberger, Accumulation of DSBs in {gamma}-H2AX domains fuel chromosomal aberrations Biochemical and Biophysical Research Communications. ,vol. 371, pp. 694- 697 ,(2008) , 10.1016/J.BBRC.2008.04.127
Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr, Vessela S. Ivanova, William M. Bonner, DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139 Journal of Biological Chemistry. ,vol. 273, pp. 5858- 5868 ,(1998) , 10.1074/JBC.273.10.5858
Monika Podhorecka, Andrzej Skladanowski, Przemyslaw Bozko, H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy Journal of Nucleic Acids. ,vol. 2010, pp. 944- 945 ,(2010) , 10.4061/2010/920161