ITPR1 autoimmunity: Frequency, neurologic phenotype, and cancer association
作者： Nora Alfugham , Avi Gadoth , Vanda A. Lennon , Lars Komorowski , Madeleine Scharf
DOI: 10.1212/NXI.0000000000000418
关键词:
摘要: Autoantibodies specific for the neuronal (type 1) isoform of ubiquitously expressed inositol trisphosphate receptor (ITPR) have been reported in 8 patients to date, 5 with cerebellar ataxia (1 breast cancer) and 3 peripheral neuropathy lung carcinoma 1 multiple myeloma).1–4 We report this study frequency, neurologic presentations, oncologic associations 14 ITPR1-immunoglobulin G (IgG)-positive patients. Acknowledgment: The authors thank John Schmeling technical support Mary Curtis secretarial assistance.
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