Bioengineered Allogeneic Blood Vessel

作者: Michael Olausson , Suchitra Sumitran-Holgersson

DOI:

关键词:

摘要: The present invention relates to methods for recellurization of blood vessels. This method is particularly useful producing an allogeneic vein, wherein a donor vein decellularized and then recellularized using whole or bone marrow stem cells. produced by the disclosed herein are advantageous implantation transplantation into patients with vascular diseases.

参考文章(17)
Michael Olausson, Pradeep B Patil, Vijay Kumar Kuna, Priti Chougule, Nidia Hernandez, Ketaki Methe, Carola Kullberg-Lindh, Helena Borg, Hasse Ejnell, Suchitra Sumitran-Holgersson, Transplantation of an allogeneic vein bioengineered with autologous stem cells: a proof-of-concept study The Lancet. ,vol. 380, pp. 230- 237 ,(2012) , 10.1016/S0140-6736(12)60633-3
Tony Karram, Aaron Hoffman, Marcelle Machluf, Nitsan Dahan, Gabriel Zarbiv, Udi Sarig, Porcine Small Diameter Arterial Extracellular Matrix Supports Endothelium Formation and Media Remodeling Forming a Promising Vascular Engineered Biograft Tissue Engineering Part A. ,vol. 18, pp. 411- 422 ,(2012) , 10.1089/TEN.TEA.2011.0173
Min Zhou, Zhao Liu, Kun Li, Wei Qiao, Xuefeng Jiang, Feng Ran, Tong Qiao, Changjian Liu, Beneficial effects of granulocyte‐colony stimulating factor on small‐diameter heparin immobilized decellularized vascular graft Journal of Biomedical Materials Research Part A. ,vol. 95, pp. 600- 610 ,(2010) , 10.1002/JBM.A.32864
Takayuki Asahara, Toyoaki Murohara, Alison Sullivan, Marcy Silver, Rien van der Zee, Tong Li, Bernhard Witzenbichler, Gina Schatteman, Jeffrey M. Isner, Isolation of putative progenitor endothelial cells for angiogenesis. Science. ,vol. 275, pp. 964- 967 ,(1997) , 10.1126/SCIENCE.275.5302.964
Seung-Woo Cho, Sang Hyun Lim, Il-Kwon Kim, Yoo Sun Hong, Sang-Soo Kim, Kyung Jong Yoo, Hyun-Young Park, Yangsoo Jang, Byung Chul Chang, Cha Yong Choi, Ki-Chul Hwang, Byung-Soo Kim, Small-diameter blood vessels engineered with bone marrow-derived cells. Annals of Surgery. ,vol. 241, pp. 506- 515 ,(2005) , 10.1097/01.SLA.0000154268.12239.ED
G. Punshon, K. M. Sales, D. S. Vara, G. Hamilton, A. M. Seifalian, Assessment of the potential of progenitor stem cells extracted from human peripheral blood for seeding a novel vascular graft material. Cell Proliferation. ,vol. 41, pp. 321- 335 ,(2008) , 10.1111/J.1365-2184.2008.00523.X
Anthony Atala, Methods and compositions for organ decellularization Official Gazette of the United States Patent and Trademark Office Patents. ,(2000)
Yilin Zhao, Su Zhang, Jianyin Zhou, Jinling Wang, Maochuan Zhen, Yun Liu, Jibing Chen, Zhongquan Qi, The development of a tissue-engineered artery using decellularized scaffold and autologous ovine mesenchymal stem cells Biomaterials. ,vol. 31, pp. 296- 307 ,(2010) , 10.1016/J.BIOMATERIALS.2009.09.049
David Simper, Paul G. Stalboerger, Carmelo J. Panetta, Shaohua Wang, Noel M. Caplice, Smooth Muscle Progenitor Cells in Human Blood Circulation. ,vol. 106, pp. 1199- 1204 ,(2002) , 10.1161/01.CIR.0000031525.61826.A8