Serum Uric Acid is a Marker of Inflammation and a Marker Predicting the Risk of Developing CVD, Stroke, Renal Failure and Cancer

摘要: Uric acid (UA) is converted from xanthine, the degradation product of purine nucleotides, by enzyme xanthine oxidase (XO). Because hyperuricemia can be induced not only inflammatory risk factors but also associated with generation new acute and chronic inflammation, therefore, elevation uric in blood (hyperuricemia) considered as a sensitive marker underlying inflammation taking place at various site body. In addition, anti-inflammatory medications have been shown to reduce level serum acid. As expected, are detectable almost all diseases. It should noted that factor rather signaling presence for development severe clinical complications. because most damages found caused directly UA superoxide free radical produced same time XO. has weak predictor cardiovascular disease general asymptomatic population significant independent among subjects who high risk.