Renal Involvement in Visceral Leishmaniasis

作者: Margarida Dutra , Reinaldo Martinelli , Edgar Marcelino de Carvalho , Luiz Erlon Rodrigues , Edilson Brito

DOI: 10.1016/S0272-6386(85)80034-2

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摘要: In a prospective study of 50 patients with visceral leishmaniasis, laboratory abnormalities suggestive renal involvement were not infrequent. Proteinuria and/or microscopic hematuria or pyuria observed in 51% such cases. Twenty-four hour urinary protein excretion was elevated 57% all cases below 1g/24. hours. An abnormal acid-load test demonstrated 12 18 studied before therapy the parasitic infection N-methyl-glucamine. Of interest demonstration tubulo-interstitial histology seven studied; also, five there proliferative glomerulonephritis, usually mild, on histologic examination. general, tendency to subsidence findings within one month after specific therapy. Renal leishmaniasis mild and seemed revert cure leishmanial infection.

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