The efficacy, safety, and tolerability of antipsychotics in the elderly.

摘要: Antipsychotic medications are among the most widely prescribed class of for elderly patients. Despite their high use, few studies document efficacy, safety, and tolerability these agents in this patient population. This is unfortunate because, as a group, exceptionally sensitive to adverse effects associated with antipsychotics, particular, extrapyramidal side (EPS). The atypical antipsychotics lower propensity cause EPS need augmenting anticholinergic medication have introduced new options patients who antipsychotic therapy number psychiatric neurologic disorders psychotic manifestations. review covers pharmacologic, clinical, regulatory issues involving use that warrant consideration by practicing psychiatrist.