Polycaprolactone-b-poly(N-isopropylacrylamide) nanoparticles: Synthesis and temperature induced coacervation behavior
作者： S. Vandewalle , M. Van De Walle , S. Chattopadhyay , F.E. Du Prez
DOI: 10.1016/J.EURPOLYMJ.2017.11.027
关键词:
摘要: Abstract Poly(caprolactone)-b-poly(N-isopropylacrylamide) (PCL-b-PNIPAM) copolymers were prepared with different compositions of the individual blocks using a combination enzyme catalyzed anionic ring opening (AROP) polymerization, reversible addition fragmentation chain transfer (RAFT) polymerization and triazolinedione-diene click chemistry. Study self-assembly these block at temperatures demonstrates formation nanoparticles, characterized by thermo-responsive behavior that is strongly dependent on PNIPAM length. At elevated temperature, self-aggregation (coacervation) nanoparticles could occur, leading to larger polymer aggregates.
core.ac.uk
sci-hub.se 参考文章(51)
Michael T. Cook, Sergey K. Filippov, Vitaliy V. Khutoryanskiy, Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer Colloid and Polymer Science. ,vol. 295, pp. 1351- 1358 ,(2017) , 10.1007/S00396-017-4084-Y
Eva Blasco, Michael B. Sims, Anja S. Goldmann, Brent S. Sumerlin, Christopher Barner-Kowollik, 50th Anniversary Perspective: Polymer Functionalization Macromolecules. ,vol. 50, pp. 5215- 5252 ,(2017) , 10.1021/ACS.MACROMOL.7B00465
Mingming Li, Pengju Pan, Guorong Shan, Yongzhong Bao, Thermoresponsive poly(ϵ‐caprolactone)‐graft‐poly(N‐isopropylacrylamide) graft copolymers prepared by a combination of ring‐opening polymerization and sequential azide–alkyne click chemistry Polymer International. ,vol. 64, pp. 389- 396 ,(2015) , 10.1002/PI.4800
Smriti Singh, Dan Eugen Demco, Khosrow Rahimi, Radu Fechete, José Carlos Rodriguez-Cabello, Martin Möller, Coacervation of Elastin-Like Recombinamer Microgels. Macromolecular Rapid Communications. ,vol. 37, pp. 181- 186 ,(2016) , 10.1002/MARC.201500457
Dong-Po Song, Ying Lin, Yue Gai, Nicholas S Colella, Cheng Li, Xiao-Hui Liu, Samuel Gido, James J Watkins, None, Controlled Supramolecular Self-Assembly of Large Nanoparticles in Amphiphilic Brush Block Copolymers Journal of the American Chemical Society. ,vol. 137, pp. 3771- 3774 ,(2015) , 10.1021/JACS.5B01050
Subrata Chattopadhyay, Helmut Keul, Martin Moeller, Preparation of waterborne functional polymers using a bifunctional coupler Green Chemistry. ,vol. 15, pp. 3135- 3139 ,(2013) , 10.1039/C3GC41406J
Ruixue Liu, Michael Fraylich, Brian R. Saunders, Thermoresponsive copolymers: from fundamental studies to applications Colloid and Polymer Science. ,vol. 287, pp. 627- 643 ,(2009) , 10.1007/S00396-009-2028-X
XiaWei Wei, ChangYang Gong, MaLing Gou, ShaoZhi Fu, QingFa Guo, Shuai Shi, Feng Luo, Gang Guo, LiYan Qiu, ZhiYong Qian, Biodegradable poly(ɛ-caprolactone)–poly(ethylene glycol) copolymers as drug delivery system International Journal of Pharmaceutics. ,vol. 381, pp. 1- 18 ,(2009) , 10.1016/J.IJPHARM.2009.07.033
Pieter Espeel, Filip E. Du Prez, “Click”-Inspired Chemistry in Macromolecular Science: Matching Recent Progress and User Expectations Macromolecules. ,vol. 48, pp. 2- 14 ,(2015) , 10.1021/MA501386V
M. Heskins, J. E. Guillet, Solution Properties of Poly(N-isopropylacrylamide) Journal of Macromolecular Science, Part A. ,vol. 2, pp. 1441- 1455 ,(1968) , 10.1080/10601326808051910