The identification of five unreported lindane metabolites recovered from rat urine.

作者: R. W. Chadwick , J. J. Freal

DOI: 10.1007/BF01684805

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摘要: Previously unreported metabolites from the urine of rats fed lindane have been identified as 3,4-dichlorophenol, 2,4,6-trichlorophenol, 2,3,4,5-tetrachlorophenol, 2,3,4,6-tetrachlorophenol and 2,3,4,5,6-pentachloro-2-cyclohexen-1-ol. While 3,4-dichlorophenol is a minor metabolite, others are excreted in greater quantities than either 2,3,5- or 2,4,5-trichlorophenol, previously metabolites. The excretion tetrachlorophenols PCCOL require revision currently accepted theory regarding metabolism by mammals.

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