Growth and recovery of zebrafish embryos after developmental exposure to raw and ozonated oil sands process-affected water.

摘要: Due to the increasing volume of oil sands process-affect water (OSPW) and its toxicity aquatic organisms, it is important fully understand effects study remediation processes that will enable release environment. Ozone treatment currently being considered as a tool expedite remediation, known degrade toxic organic compounds present in OSPW. In this study, we aimed measure OSPW exposure on growth, development recovery zebrafish (Danio rerio) embryos. We also used ozone-treated determine whether ozonation negated any raw exposure. As biomarkers exposure, assessed expression genes involved neurodevelopment (ngn1, neuroD), estrogenicity (vtg), oxidative stress (sod1), biotransformation (cyp1a, cyp1b). Our found both ozonated did not impair growth embryos, however, otoliths exposed embryos were smaller than those control The levels cyp1a cyp1b induced by However, after period, these returned within two days residence clean water. no changes ngn1, neuroD vtg with treated or untreated Overall, our have many negative appeared recover relatively quickly ended. Furthermore, ozone decreased induction cyp1b.