Metabolic Variations in Manic-Depressive Psychosis

摘要: 1. The blood levels of acetylmethylcarbinol, butane-2:3-diol, pyruvate and glucose have been determined at twice-weekly intervals in a group patients exhibiting alternating manic depressive mood changes subjects without variation while under observation. In addition, the thiocyanate space 24-hour urinary excretions uric acid, creatinine also estimated frequent intervals. 2. An increase is associated with normal inter-phases showing changes. change during period investigation within limits. 3. A decrease both level excretion acetylmethylcarbinol precedes early part phase. relationship time between chemical by periodicity cycle. 4. acid/creatinine ratio decreased before association initial depressed phases.