作者: Markku Seppälä , Bruce Lessey
DOI: 10.1007/978-1-4419-8955-0_21
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摘要: Human embryo implantation normally takes place between days 20 and 24, or LH +7 +11 of a normal conception cycle. The process begins with apposition the hatched blastocyst to luminal surface epithelium endometrium is followed by adhesion, invasion anchorage trophoblast into endometrial stroma where it comes contact maternal blood vessels. Irrespective whether fertilization in vivo vitro, receptivity results from an orchestrated interplay which hormones, hormone receptors, Oligosaccharides, lectins, integrins, growth factors, cytokines, proteases their inhibitors, Prostaglandins, peptides, factors that modulate immune cell reactivity against play role. At same time, provides constraints on uncontrolled trophoblast. A receptive end result responses endocrine paracrine messages derive stimulated ovary, exogenous endometrium, embryo. For instance, poor oocyte quality may be associated inadequate follicle maturation secretion affect quality, implantation.