Nutrition in Oncology: From Treating Cachexia to Targeting the Tumor

摘要: Cancer is a disease closely linked to nutrition. In fact, unhealthy eating habits have been causally related the onset of some tumors. Also, clinical journey cancer patients characterized by profound changes in nutritional status, i.e., cachexia, as consequence impairment host’s metabolism and behavior. Finally, anticancer therapies may per se alter status inducing toxicity reduced energy intake, well favoring muscle loss. daily practice, malnutrition generally not assessed patients, nutrition therapy considered only final stages patients’ journey. This approach contrast with consistent robust evidence showing that strong predictor negative outcome cancer. Therefore, should be from very beginning Highlighting relevance preventing/treating recent trials showed when provided early within multimodal context which includes psychological support pain control, then survival extended quality life improved advanced Furthermore, experimental seem suggest use specific nutrients (i.e., omega-3 fatty acids, glutamine, arginine, branched-chain amino etc.) at key time points during an inhibitory influence on tumor growth. particular, acids shown ameliorate inflammatory microenvironment enhance response rate chemotherapy. These preliminary data need confirmation large before their translation into practice. Nevertheless, they help shift consideration oncologists toward procedure for last days component therapies.