Metal Ions, Mitochondrial DNA and Aging

作者: H. R. Massie

DOI: 10.1007/978-3-642-70853-4_11

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摘要: It has been previously proposed that accumulation of errors in or damage to genetic material might represent the initiating event cellular aging (Szilard 1959). The relationship between parental and filial life span (Falek et al. 1960), radiation-produced shortening (Lamson 1959) inverse proportionality rate germ-line mutation various species (Failla 1960) have all ascribed factors (Harman 1962).

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