Investigation of 4D PET attenuation correction using Ultra-short Echo Time MR

摘要: In hybrid imaging systems where positron emission tomography (PET) is combined with magnetic resonance (MR) imaging, attenuation maps can be derived from MR to correct for in PET. However, MR-based correction (AC) remains challenging especially tissue types showing poor signal common sequences, such as bone. To overcome this problem, Ultra-short Echo Time (UTE) sequences have been proposed. Another challenge given by respiratory motion which results misalignments between the and PET emissions. paper we address both issues. We compute a 4D map including bone combining gated UTE acquisition subject-specific model second short dynamic acquisition. demonstrate our approach on an MR-derived time-averaged simulation three healthy volunteers, artificial lesions. The impact of AC simulated excluding leading errors up 26.0%. using non-moving 3D map, error 24.2%. These indicate that consideration crucial ensure accurate AC.