作者: Hiroshi Mashiko , Hidenobu Takahashi
DOI: 10.3109/15569549809040406
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摘要: AbstractIt was revealed that almost all snake venom haemorrhagic factors (HFs) are metalloproteinases. Analysis of primary structures HFs they share multi-domain structures. And divided into four major classes. These damaged the micro blood vessel walls and cause local haemorrhage. Some systemic, organ specific species This review describes autoproteolysis HFs. Types mechanisms haemorrhage caused by also described.