CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.
作者： S M Iguchi-Ariga , W Schaffner
DOI: 10.1101/GAD.3.5.612
关键词:
摘要: … enhancer sequences inserted downstream of the [3-globin reporter gene (Fig. 5B). Treatment of the cells with forskolin or dBucAMP did not give a significant increase in expression (…
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