作者: Gaetano T. Montelione , John Francis Hunt , Gregory P. Boel , Thomas Acton , William Nicholson Price
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摘要: The invention is directed to methods and metric suitable for use in determining the solubility, expression usability of a polypeptide encoded by nucleic acid sequence. In certain aspects, also relates introducing modifications polypeptide, example through substitution one or more codons sequence encoding increase decrease polypeptide.