Mechanisms of Thrombolysis

作者: Gregory J. Zoppo , Naohisa Hosomi

DOI: 10.1385/1-59259-933-8:3

关键词:

摘要: The pharmacological use of plasminogen activators is associated with symptomatic improvement in patients coronary artery thrombosis, peripheral arterial occlusions, and thrombosis the venous system. Based on prospective angiographic studies planned programs (1, 2, 3, 4, 5), thrombolysis only approved treatment acute ischemic stroke (6, 7, 8) under limited circumstances. Currently, recombinant tissue activator (rt-PA) licensed United States several other countries for within 3 h onset (6).

参考文章(151)
M. Kaste, C. Fieschi, W. Hacke, E. Lesaffre, M. Verstraete, J. Fröhlich, The European Cooperative Acute Stroke Study (ECASS) Springer, Berlin, Heidelberg. pp. 66- 71 ,(1993) , 10.1007/978-3-642-78061-5_10
G Nicoloso, C Genton, H Welti, F Bachmann, EK Kruithof, C Tran-Thang, A Gudinchet, J Hauert, Fibrinolysis in pregnancy: a study of plasminogen activator inhibitors. Blood. ,vol. 69, pp. 460- 466 ,(1987) , 10.1182/BLOOD.V69.2.460.460
Alkjaersig N, Genton E, Hirsh J, Fletcher Ap, Sherry S, Bachmann F, THE DEVELOPMENT OF UROKINASE AS A THROMBOLYTIC AGENT. MAINTENANCE OF A SUSTAINED THROMBOLYTIC STATE IN MAN BY ITS INTRAVENOUS INFUSION. Journal of Laboratory and Clinical Medicine. ,vol. 65, pp. 713- ,(1965)
G J del Zoppo, E G Levin, Localization of tissue plasminogen activator in the endothelium of a limited number of vessels American Journal of Pathology. ,vol. 144, pp. 855- 861 ,(1994)
N Alkjaersig, AP Fletcher, Catabolism and excretion of fibrinopeptide-A Blood. ,vol. 60, pp. 148- 156 ,(1982) , 10.1182/BLOOD.V60.1.148.148
T Suyama, K Fujikawa, A Ichinose, The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin. Journal of Biological Chemistry. ,vol. 261, pp. 3486- 3489 ,(1986) , 10.1016/S0021-9258(17)35674-0
J.P. Miletich, C.M. Jackson, P.W. Majerus, Properties of the factor Xa binding site on human platelets. Journal of Biological Chemistry. ,vol. 253, pp. 6908- 6916 ,(1978) , 10.1016/S0021-9258(17)38006-7