作者: Kazuyoshi Hirota
DOI: 10.1007/S00540-020-02814-7
关键词:
摘要: Angiotensin converting enzyme 2 (ACE2) is a target cell receptor for internalization and proliferation of the severe acute respiratory syndrome coronavirus (SARS-CoV-2). When ACE2-highly expressed tissues are manipulated, SARS-CoV-2 containing aerosols may be generated. Normal breathing speaking capable producing so mask ventilation, suction airway tract bucking during tracheal intubation extubation clinical procedures significant aerosol production. Whilst no data have been reported on distribution in operating room (OR), contamination OR can estimated from intensive care unit (ICU) data. ICU showed that was detected all types surface air within about 4 m disease 2019 (COVID-19) patients. High concentrations personal protective equipment (PPE) removal medical staff office. Submicron virus-laden could result resuspension particles sticking PPE surface; produce initial velocity. Supermicron come floor deposited SARS-CoV-2, which were carried across different areas by (e.g., shoe). Knowledge generation will aid design strategies to reduce transmission risk.