Ependymoma: new therapeutic approaches including radiation and chemotherapy.

摘要: Recent advances in neuroimaging, neurosurgery and radiation therapy have improved disease control functional outcomes for children with ependymoma, including under the age of 3 years. The rate gross-total resection has been increased to 85% some series year progression-free survival after as high 75% reported along significant reductions neurologic, endocrine cognitive deficits. Based on these renewed interest a frontline treatment modality, attention refocused instead radiotherapy avoidance. Future research this tumor, that afflicts fewer than 200 US each year, will focus molecular biology, clarifying risk factors tumor late effects, testing novel agents.