摘要: Fluid mechanics plays a key role in the development, progression, and treatment of cardiovascular disease. Advances imaging methods patient-specific modeling now reveal increasingly detailed information about blood flow patterns health Building on these tools, there is an opportunity to couple simulation with optimization algorithms improve design surgeries devices, incorporating more physics process augment current medical knowledge. In doing so, major challenge need for efficient tools that are appropriate unsteady fluid problems, particularly complex models presence uncertainty. This article reviews state art virtual surgery, device design, model parameter identification mechanobiology applications. particular, it trade-offs between traditional ...