Stem cells and gliomas: past, present, and future.
作者： Isabelle M. Germano , Emanuela Binello
DOI: 10.1007/S11060-014-1498-Y
关键词:
摘要: The recognition of stem cells (SC) in the adult CNS and association with gliomas has spawned an entire field research intense investigation. A large body knowledge is being accumulated to gain insight into pathobiology intent finally improving grave prognosis that continues beset patients high grade (HGG). In this article, we provide a historical overview events leading discovery SC glioma (GSC). We then focus on current understanding GSC respect markers, clinical significance, their targeting. discuss data developments using as vehicles delivery therapeutic agents HGG. conclude discussion opportunities for future development concepts aimed at reducing tumor recurrence survival
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