作者: E. Franek , E. Klamczynska , E. Ganowicz , A. Blach , T. Budlewski
DOI: 10.1038/AJH.2008.330
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摘要: BACKGROUND The aim of the study was to answer question whether chronic periodontitis (CP) in patients with essential hypertension is associated increased aortic stiffness and central blood pressure (CBP), which may turn increase left ventricular mass (LVM) those patients. CP influences LVM hypertensive renal as well healthy subjects; however, mechanisms involved are not clear. METHODS Fifty (23 men 27 women, 51.4 +/- 5.2 years, body index (BMI) 29.5 4.4 kg/m(2)) severe CP-Community Periodontal Index Treatment Needs (CPITN) score 3-4, 49 (20 29 49.3 5.5 BMI 29.9 4.8 no or moderate (CPITN 0-2) were included. In all LVM, pulse wave velocity (PWV), CBP measured, (LVMI) calculated. RESULTS Patients a CPITN 3-4 had higher (257.3 67.9 vs. 220.3 66.4 g, P < 0.01), LVMI (105.8 23.6 92.6 24.8 g/m(2), 0.01) systolic (124 17 116 15 mm Hg, 0.05) (45 11 38.7 9.8 compared 0-2. univariate analysis, for total group positive association observed between values LVMI, age, systolic, pressure, but systemic pressure. Linear regression analysis showed an borderline significance (P = 0.06) value. other model, significant relationship observed. CONCLUSIONS More forms primary hypertension.