Depressive dementia: a "transitional dementia"?

摘要: This review comprises a historical, clinical, and empirical examination of the dementia spectrum depression. The primary focus article is to evaluate usual dichotomy between depressive as functional-reversible degenerative organic-irreversible. It proposed that depression, cognitive impairment, be viewed intersecting continua. Five prototypical groups are defined along these continua: (1) major depression without dementia, (2) (3) (4) (5) random co-occurrence dementia. data suggest subset cases appear evolve into in turn, may constitute risk factor for Depressive can sometimes represent two different points organic deterioration severity long-term, multiphasic disease course; appears transitional stage or phase progression from concept "transitional dementia" introduced heuristic preliminary attempt accommodate nosologic entity