Gut flora and bacterial translocation in chronic liver disease

摘要: Increasing evidence suggests that derangement of gut flora is substantial clinical relevance to patients with cirrhosis. Intestinal bacterial overgrowth and increased translocation from the intestinal lumen, in particular, predispose an potential for infection this group. Recent studies suggest that, addition their role pathogenesis overt infective episodes consequences sepsis, contributes pro-inflammatory state cirrhosis even absence infection. Furthermore, manipulation augment content lactic acid-type bacteria at expense other species more pathogenic may favourably influence liver function cirrhotic patients. Here we review current concepts various inter-relationships between flora, translocation, infection, cytokine production