Review of all studies of cardiopulmonary resuscitation in animal models reported in the emergency medicine literature for the past 10 years

摘要: This study involved a review of all the research studies cardiopulmonary resuscitation (CPR) in animal models reported American emergency medicine literature for past 10 years (January 1981 through December 1990). The objectives present were to discern any evident trends this research, determine what aspects these not standardized, identify procedural problems with studies, and compare number journals other medical journals. A recommendations about techniques human CPR have been extrapolated directly from without testing adequately humans. Perhaps best example is Heart Association’s recommendation that 1 mg epinephrine standard dose use adult based on Redding’s original using doses lo-kg weight dogs.’ dosage was accepted critical reevaluation humans very long time until recent realization may incorrectly studies. stimulated flurry interest “high-dose” epinephrine, conducted humans.2-8 Other which reached differing conclusions include effectiveness bicarbonate,9“2 relative different agents resuscitation, ‘“,‘3-19 whether “early” improves survival. 20*2’ These differences or outcomes reflect used rather than true parameter studied.