作者: Tugba Kilic , Arzum Erdem , Mehmet Ozsoz , Sandro Carrara
DOI: 10.1016/J.BIOS.2017.08.007
关键词:
摘要: As being the most extensively studied, non-coding, evolutionary conserved, post-transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention among various disciplines due to their important roles in biological processes and link with cancer. Due diagnostic value, there been many conventional methods used detection miRNAs including northern blotting, quantitative real time PCR (qRT-PCR) microarray technology besides novel techniques based on nanotechnology approaches molecular biology tools miRNA biosensors. The aim this review is explain importance biomedical field an emphasis early cancer diagnosis by overviewing both research commercially available last decade considering strengths weakness