An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya

摘要: The neglected zoonotic diseases (NZD) are an understudied group that a major cause of illness throughout the developing world. In general, little is known about prevalence and burden NZDs in affected communities, particularly relation to other infectious with which they often co-endemic. We describe design descriptive epidemiological outputs from integrated study human animal non-zoonotic disease rural farming community western Kenya. This cross-sectional survey involved 2113 people, their cattle (n = 983) pigs (n = 91). People animals were tested for infection or exposure wide range pathogens. Prevalence estimates, adjustment complex design, derived. Evidence spatial clustering was identified using scan statistic. There high parasitism community, hookworm (Ancylostoma duodenale Necator americanus) (36.3% (95% CI 32.8–39.9)), Entamoeba histolytica/dispar (30.1% 27.5–32.8)), Plasmodium falciparum (29.4% 26.8–32.0)). Human Taenia spp. also prevalent (19.7% 16.7–22.7)), while pathogens comparatively rarer (Brucella spp., 0.6% 0.2–0.9); Coxiella burnetii, 2.2% 1.5–2.9); Rift Valley fever, 0.5% 0.2–0.8)). A low Brucella observed (0.26% 0–0.56). higher fever virus (1.4% 0.5–2.22)) C. burnetii (10.0% 7.7–12.2)). cysticercosis 53.5% 48.7–58.3) 17.2% 9.1–25.3) pigs. Mycobacterium bovis found 1.3–3.2), 8.2% 6.8–9.6) people. Zoonotic infections people occur context co-endemic diversity under provides unique opportunity explore distribution determinants multi-pathogen, multi-host system.