Macrophages and Translymphatic Absorption Represent the First Line of Host Defense of the Peritoneal Cavity

摘要: • To quantitate the host defenses of rat peritoneal cavity, nonviable radiolabeled Escherichia coli were injected intraperitoneally and clearance, leukocyte influx, phagocytosis examined. Macrophages (MCs) present initially remained relatively constant in number. The polymorphonuclear (PMN) response began at one to two hours was maximal 24 72 hours. A previously unidentified inoculum-dependent PMN defined. Clearance extremely rapid, few ( Arch Surg 1987;122:105-110)