Abnormal Functional Activity of the Central Nervous System in Fibromyalgia Syndrome

摘要: The evaluation of pain is one the major problems facing general practitioners and specialists in medicine. Although source can be usually traced to specific abnormalities a given organ system, some patients present with generalized syndromes, such as fibromyalgia, for which no found. Some researchers have begun consider that although there may somatic at its initiation, over time maintained or exacerbated by functional alterations critical regions brain spinal cord are involved processing inhibition. This article describes techniques currently used measure regional cerebral blood flow (rCBF) single photon emission computed tomography (SPECT) imaging, reviews SPECT positron literature concerning activity associated healthy individuals chronic pain, including those fibromyalgia. concludes describing implications current knowledge about abnormal understanding pathophysiology fibromyalgia development therapeutic strategies manage this disorder.