Chronic cyclosporine nephrotoxicity
作者： Takeshi F. Andoh , William M. Bennett
DOI: 10.1097/00041552-199805000-00005
关键词:
摘要: Cyclosporine has improved patient and graft survival rates in solid organ transplantation, been increasingly applied with considerable clinical benefit the treatment of autoimmune diseases. However, therapeutic benefits immunosuppressive therapy for transplant indications have frequently limited by occurrence chronic nephrotoxicity. nephrotoxicity therefore remains an important challenge. The aspects pathophysiology cyclosporine nephrotoxicity, which is characterized a decrease glomerular filtration rate, afferent arteriolopathy, striped tubulointerstitial fibrosis, are reviewed. Insights gained from experimental models associated fibrosis presented to elucidate pathophysiology.
elsevier.com
sci-hub.se 参考文章(27)
D. Serur, W. T. Stubenbord, G. T. Shin, M. Suthanthiran, K. H. Stenzel, A. L. Rubin, J. C. L. Wang, R. R. Riggio, J. S. Cheigh, Effect of nifedipine on renal allograft function and survival beyond one year. Clinical Nephrology. ,vol. 47, pp. 33- 36 ,(1997)
Takeshi F. Andoh, Jessie Lindsley, Nora Franceschini, William M. Bennett, Synergistic effects of cyclosporine and rapamycin in a chronic nephrotoxicity model Transplantation. ,vol. 62, pp. 311- 316 ,(1996) , 10.1097/00007890-199608150-00002
Ronald G. Thurman, Zhi Zhong, Moritz von Frankenberg, Robert F. Stachlewitz, Hartwig Bunzendahl, Prevention of cyclosporine-induced nephrotoxicity with dietary glycine. Transplantation. ,vol. 63, pp. 1661- 1667 ,(1997) , 10.1097/00007890-199706150-00021
Lothar Aicher, Gabriele Meier, Alastair J. Norcross, Joseph Jakubowski, Maria Del Carmen Varela, André Cordier, Sandra Steiner, Decrease in kidney calbindin-D 28kDa as a possible mechanism mediating cyclosporine A- and FK-506-induced calciuria and tubular mineralization. Biochemical Pharmacology. ,vol. 53, pp. 723- 731 ,(1997) , 10.1016/S0006-2952(96)00772-1
Christopher Chan, Janet Maurer, Carl Cardella, Dan Cattran, York Pei, A randomized controlled trial of verapamil on cyclosporine nephrotoxicity in heart and lung transplant recipients. Transplantation. ,vol. 63, pp. 1435- 1440 ,(1997) , 10.1097/00007890-199705270-00012
Raimund H. Pichler, Christian Hugo, Stuart J. Shankland, May J. Reed, James A. Bassuk, Takeshi F. Andoh, Donna M. Lombardi, Stephen M. Schwartz, William M. Bennett, Charles E. Alpers, E. Helene Sage, Richard J. Johnson, William G. Couser, SPARC is expressed in renal interstitial fibrosis and in renal vascular injury Kidney International. ,vol. 50, pp. 1978- 1989 ,(1996) , 10.1038/KI.1996.520
Takeshi F. Andoh, Emmanuel A. Burdmann, Nora Fransechini, Donald C. Houghton, William M. Bennett, Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506 Kidney International. ,vol. 50, pp. 1110- 1117 ,(1996) , 10.1038/KI.1996.417
S??nia M. A. Assis, Jos?? L. Monteiro, Antonio C. Seguro, L-Arginine and allopurinol protect against cyclosporine nephrotoxicity. Transplantation. ,vol. 63, pp. 1070- 1073 ,(1997) , 10.1097/00007890-199704270-00004
Daniel J. Goldstein, Nancy Zuech, Vinita Sehgal, Alan D. Weinberg, Ronald Drusin, David Cohen, Cyclosporine-associated end-stage nephropathy after cardiac transplantation: incidence and progression. Transplantation. ,vol. 63, pp. 664- 668 ,(1997) , 10.1097/00007890-199703150-00009
Fuad S. Shihab, William M. Bennett, Amie M. Tanner, Takeshi F. Andoh, Angiotensin II blockade decreases TGF-β1 and matrix proteins in cyclosporine nephropathy Kidney International. ,vol. 52, pp. 660- 673 ,(1997) , 10.1038/KI.1997.380