Toxic epidermal necrolysis due to voriconazole: case report and review.

摘要: Toxic epidermal necrolysis is an uncommon but potentially life-threatening adverse cutaneous drug reaction characterized by variable degrees of necrosis and detachment leading to morbidity risk mortality. We describe a 67-year-old woman who underwent allogeneic peripheral blood stem cell transplantation as treatment for chronic lymphocytic leukemia. She developed toxic after she was transitioned voriconazole, which component her post-transplant regimen. The diagnosis in our patient made clinically confirmed histologically. Based on the temporal initiation voriconazole therapy development reaction, we concluded that offending agent. There are limited reported cases voriconazole-induced necrolysis; report this case increase awareness potential complication.