Chemical Profile and Cytotoxic Activity of Leaf Extracts from Senna spp. from Northeast of Brazil

摘要: Methanolic, diethyl ether and n-hexane extracts of leaves four species Senna (S. gardneri, S. macranthera, splendida trachypus) were analyzed by gas chromatography coupled to mass spectrometry (GC-MS). Using linear retention indices spectral data, 34 compounds identified, including fatty acids, flavonoids, terpenoids steroids that not reported previously for these species. Additionally, the cytotoxicity against different tumor cell lines was determined. The then correlated with chemical composition partial least squares-discriminant analysis (PLS-DA). extract gardneri ethyl most active human colon (59.75 31.37%, respectively) glioblastoma (52.85 48.28%, lines.