Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma.

作者: Nagjie Alijaj , Sandrine Moutel , Zelia L. Gouveia , Maxim Gray , Maurizio Roveri

DOI: 10.3390/CANCERS12113313

关键词:

摘要: … libraries, the humanized VHH library NaLi-H1 [36] and the … revealed 24 phage clones from NaLi-H1 library and 55 phage … 12 unique sdAb from the NaLi-H1 library and 28 from the …

参考文章(58)
Seishi Ogawa, Junko Takita, Masafumi Seki, Riki Nishimura, Kenichi Yoshida, Teppei Shimamura, Yuichi Shiraishi, Yusuke Sato, Motohiro Kato, Kenichi Chiba, Hiroko Tanaka, Noriko Hoshino, Genta Nagae, Yusuke Shiozawa, Yusuke Okuno, Hajime Hosoi, Yukichi Tanaka, Hajime Okita, Mitsuru Miyachi, Ryota Souzaki, Tomoaki Taguchi, Katsuyoshi Koh, Ryoji Hanada, Keisuke Kato, Yuko Nomura, Masaharu Akiyama, Akira Oka, Takashi Igarashi, Satoru Miyano, Hiroyuki Aburatani, Yasuhide Hayashi, Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma Nature Communications. ,vol. 6, pp. 7557- 7557 ,(2015) , 10.1038/NCOMMS8557
Clément Nizak, Sandrine Moutel, Bruno Goud, Franck Perez, Selection and application of recombinant antibodies as sensors of rab protein conformation. Methods in Enzymology. ,vol. 403, pp. 135- 153 ,(2005) , 10.1016/S0076-6879(05)03012-0
Xin Sun, Wei Guo, Jacson K. Shen, Henry J. Mankin, Francis J. Hornicek, Zhenfeng Duan, Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. Sarcoma. ,vol. 2015, pp. 232010- 232010 ,(2015) , 10.1155/2015/232010
Sivasubramanian Baskar, Nityashree Shivaprasad, Zhongyu Zhu, Dimiter Dimitrov, Mhairi Sigrist, Poul Sorensen, Marielle Yohe, John Shern, John Maris, Crystal Mackall, Javed Khan, Abstract 2488: FGFR4 as a potential therapeutic target for monoclonal antibody based intervention in rhabdomyosarcoma Cancer Research. ,vol. 75, pp. 2488- 2488 ,(2015) , 10.1158/1538-7445.AM2015-2488
Javed Khan, Jun S Wei, Markus Ringner, Lao H Saal, Marc Ladanyi, Frank Westermann, Frank Berthold, Manfred Schwab, Cristina R Antonescu, Carsten Peterson, Paul S Meltzer, None, Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks Nature Medicine. ,vol. 7, pp. 673- 679 ,(2001) , 10.1038/89044
Theresa M Allen, Puja Sapra, Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Research. ,vol. 62, pp. 7190- 7194 ,(2002)
Preeti Kumari, Balaram Ghosh, Swati Biswas, Nanocarriers for cancer-targeted drug delivery. Journal of Drug Targeting. ,vol. 24, pp. 179- 191 ,(2016) , 10.3109/1061186X.2015.1051049
Teresa Helsten, Maria Schwaederle, Razelle Kurzrock, Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications Cancer and Metastasis Reviews. ,vol. 34, pp. 479- 496 ,(2015) , 10.1007/S10555-015-9579-8
Hillary G. Caruso, Lenka V. Hurton, Amer Najjar, David Rushworth, Sonny Ang, Simon Olivares, Tiejuan Mi, Kirsten Switzer, Harjeet Singh, Helen Huls, Dean A. Lee, Amy B. Heimberger, Richard E. Champlin, Laurence J.N. Cooper, Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity Cancer Research. ,vol. 75, pp. 3505- 3518 ,(2015) , 10.1158/0008-5472.CAN-15-0139