Síndrome colestásico neonatal prolongado secundario a panhipopituitarismo. Informe de un caso y revisión de la literatura

作者: Flora Zárate-Mondragón , Roberto Cervantes-Bustamante , Jaime Ramírez-Mayans , Erika Montijo-Barrios , Erick Manuel Toro-Monjaraz

DOI: 10.18233/APM33NO3PP154-157

关键词:

摘要: Prolonged neonatal cholestasis syndrome has several etiologies, some of them are endocrinological; one these includes hypopituitarism which is infrequent and whose incidence unknown. Although isolated cases have been reported worldwide, there no reports in Mexico. We present the case a 28 day-old male who was admitted to our service with hypoglycemia. A hypophyseal hormone deficiency documented. Hormone replacement therapy started, resulted remission symptomatology. Physiopathology unclear. However, it believed that deficit growth may alter liver function decreasing biliary salt synthesis altering duct structure. The importance this stems from fact etiology should be intentionally

参考文章(11)
Daniel DeSalvo, John F. Pohl, Don P. Wilson, William Bryant, David Easley, John Greene, Jose Santiago, Cholestasis secondary to panhypopituitarism in an infant. Journal of The National Medical Association. ,vol. 100, pp. 342- 344 ,(2008) , 10.1016/S0027-9684(15)31249-9
F R Kaufman, G Costin, D W Thomas, F R Sinatra, T F Roe, H B Neustein, Neonatal cholestasis and hypopituitarism. Archives of Disease in Childhood. ,vol. 59, pp. 787- 789 ,(1984) , 10.1136/ADC.59.8.787
Juan Javier Lammoglia, Francisca Eyzaguirre, Nancy Unanue, Rossana Román, Ethel Codner, Fernando Cassorla, Verónica Mericq, [Congenital hypopituitarism: report of 23 cases]. Revista Medica De Chile. ,vol. 136, pp. 996- 1006 ,(2008) , 10.4067/S0034-98872008000800006
A. G. Sheehan, S. R. Martin, D. Stephure, R. B. Scott, Neonatal cholestasis, hypoglycemia, and congenital hypopituitarism. Journal of Pediatric Gastroenterology and Nutrition. ,vol. 14, pp. 426- 430 ,(1992) , 10.1097/00005176-199205000-00009
Stephen P. Herman, Archie H. Baggenstoss, Mark D. Cloutier, Liver dysfunction and histologic abnormalities in neonatal hypopituitarism. The Journal of Pediatrics. ,vol. 87, pp. 892- 895 ,(1975) , 10.1016/S0022-3476(75)80900-0
G. Binder, D.D. Martin, I. Kanther, C.P. Schwarze, M.B. Ranke, The course of neonatal cholestasis in congenital combined pituitary hormone deficiency. Journal of Pediatric Endocrinology and Metabolism. ,vol. 20, pp. 695- 702 ,(2007) , 10.1515/JPEM.2007.20.6.695
Antoine Leblanc, Michel Odièvre, Michelle Hadchouel, Dominique Gendrel, Jean-Louis Chaussain, Raphaël Rappaport, Neonatal cholestasis and hypoglycemia: Possible role ofcortisol deficiency The Journal of Pediatrics. ,vol. 99, pp. 577- 580 ,(1981) , 10.1016/S0022-3476(81)80260-0
C. J. ELLAWAY, M. SILINK, C. T. COWELL, K. J. GASKIN, K. R. KAMATH, S. DORNEY, K. C. DONAGHUE, Cholestatic jaundice and congenital hypopituitarism. Journal of Paediatrics and Child Health. ,vol. 31, pp. 51- 53 ,(1995) , 10.1111/J.1440-1754.1995.TB02914.X
A. Nyunt, Adult cirrhosis due to untreated congenital hypopituitarism. Journal of the Royal Society of Medicine. ,vol. 98, pp. 316- 317 ,(2005) , 10.1258/JRSM.98.7.316
Supawadee Likitmaskul;, Jeerunda Santiprabhob;, Prapun Aanpreung, Wikrom Karnsakul;, Pairunyar Sawathiparnich;, Saroj Nimkarn;, Anterior pituitary hormone effects on hepatic functions in infants with congenital hypopituitarism Annals of Hepatology. ,vol. 6, pp. 97- 103 ,(2007) , 10.1016/S1665-2681(19)31939-8