Treatments for Depression in Older Persons with Dementia

作者: Kimberly P McClive-Reed , Zvi D Gellis , Ellen Brown

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摘要: A wide range of pharmacological and nonpharmacological treatments have been used to relieve depression in persons with cognitive impairment dementia. Clinical consensus research appear support SSRIs as a first choice for the treatment In nonresponsive or special needs patients, other drugs used, including antipsychotics, anticholinergics, anticonvulsants, memantine, complementary/alternative medications. Extra care is required prescribing this population, due generally high level medical psychiatric comorbidity potential difficulty assessing cognitively impaired patient’s response. Nonpharmacologic interventions emotion-oriented therapies, behavioral cognitive-behavioral modification programs, structured activity programs demonstrate initial treating depression, anxiety, BPSD. Sensory stimulation therapies such art/music therapy, aromatherapy, animal-assisted/pet massage/touch multisensory approaches show some promise successful dementia, but further more rigorous needed establish their validity.

参考文章(90)
Lori A. Daiello, Current issues in dementia pharmacotherapy. The American Journal of Managed Care. ,vol. 13, ,(2007)
Sarah Thompson, Nathan Herrmann, Mark J Rapoport, Krista L Lanctôt, Efficacy and safety of antidepressants for treatment of depression in Alzheimer's disease: a metaanalysis. The Canadian Journal of Psychiatry. ,vol. 52, pp. 248- 255 ,(2007) , 10.1177/070674370705200407
Nathan Herrmann, Krista L Lanctôt, Pharmacologic Management of Neuropsychiatric Symptoms of Alzheimer Disease The Canadian Journal of Psychiatry. ,vol. 52, pp. 630- 646 ,(2007) , 10.1177/070674370705201004
Lee Hb, Valenti A, Roy P, Appleby Bs, Diagnosis and treatment of depression in Alzheimer's disease: impact on mood and cognition Panminerva Medica. ,vol. 49, pp. 139- 149 ,(2007)
Dilip V Jeste, John P Docherty, George S Alexopoulos, Daniel Carpenter, Henry Chung, Ruth Ross, The expert consensus guideline series. Treatment of dementia and its behavioral disturbances. Introduction: methods, commentary, and summary. Postgraduate Medicine. pp. 6- 22 ,(2005)
Gerald Nestadt, Gregory L. Hanna, Helen Blair Simpson, Eric Hollander, Lorrin M. Koran, Practice guideline for the treatment of patients with obsessive-compulsive disorder. American Journal of Psychiatry. ,vol. 164, pp. 5- 53 ,(2007)
Cooper Jp, Buspirone for anxiety and agitation in dementia. Journal of Psychiatry & Neuroscience. ,vol. 28, pp. 469- 469 ,(2003)
Niels Viggo Hansen, Torben Jørgensen, Lisbeth Ørtenblad, Massage and touch for dementia. Cochrane Database of Systematic Reviews. ,vol. 2006, ,(2006) , 10.1002/14651858.CD004989.PUB2
Martin Neal, Philip Barton Wright, Validation therapy for dementia Cochrane Database of Systematic Reviews. ,(2003) , 10.1002/14651858.CD001394