Platform for targeted delivery to stem cells and tumor cells and methods thereof
作者： Ligia Catarina Gomes Da Silva , Joao Nuno Sereno De Almeida Moreira , Sergio Paulo De Magalhaes Simoes , Nuno Andre Carvalho Da Fonseca , Vera Lucia Dantas Nunes Caldeira De Moura
DOI:
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摘要: The invention involves therapy and diagnostics using nanoparticles that provide targeted delivery of agents to cancer cells stem cells,including cells, the being pH sensitive incorporating cytotoxic ceramides.
lens.org 参考文章(84)
Rebecca J. Watters, Mark Kester, Melissa A. Tran, Thomas P. Loughran, Xin Liu, Development and Use of Ceramide Nanoliposomes in Cancer Methods in Enzymology. ,vol. 508, pp. 89- 108 ,(2012) , 10.1016/B978-0-12-391860-4.00005-7
João N. Moreira, Tatsuhiro Ishida, Rogério Gaspar, Theresa M. Allen, Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity. Pharmaceutical Research. ,vol. 19, pp. 265- 269 ,(2002) , 10.1023/A:1014434732752
Ting-Chao Chou, The mass-action law based algorithm for cost-effective approach for cancer drug discovery and development. American Journal of Cancer Research. ,vol. 1, pp. 925- 954 ,(2011)
Enid Choi, Paula J. Bates, Methods and products to target, capture and characterize stem cells ,(2008)
Maria da Conceição Monteiro Pedroso de Lima, João Nuno Sereno de Almeida Moreira, Sergio Paulo de Magalhães Simões, Vera Lúcia Dantas Nunes Caldeira de Moura, Targeted delivery to human diseases and disorders ,(2012)
Daniel Canals, David M Perry, Russell W Jenkins, Yusuf A Hannun, Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases. British Journal of Pharmacology. ,vol. 163, pp. 694- 712 ,(2011) , 10.1111/J.1476-5381.2011.01279.X
Si-Shen Feng, Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. International Journal of Nanomedicine. ,vol. 1, pp. 297- 315 ,(2006) , 10.2217/17435889.1.3.297
Sriram S. Shanmugavelandy, Todd Fox, Mark Kester, Ceramide anionic liposome compositions ,(2012)
Yusuf A. Hannun, Lina M. Obeid, Principles of bioactive lipid signalling: lessons from sphingolipids Nature Reviews Molecular Cell Biology. ,vol. 9, pp. 139- 150 ,(2008) , 10.1038/NRM2329
Jinhao Gao, Kai Chen, Renguo Xie, Jin Xie, Yongjun Yan, Zhen Cheng, Xiaogang Peng, Xiaoyuan Chen, In Vivo Tumor-Targeted Fluorescence Imaging Using Near-Infrared Non-Cadmium Quantum Dots Bioconjugate Chemistry. ,vol. 21, pp. 604- 609 ,(2010) , 10.1021/BC900323V