Issues in the incorporation of economic perspectives and evidence into Cochrane reviews

摘要: Background: Methods for systematic reviews of the effects health interventions have focused mainly on addressing question 'What works?' or 'Is this intervention effective in achieving one more specific outcomes?' Addressing it worth given resources available?' has received less attention. This latter can be addressed by applying an economic lens to review process. paper reflects value and desire consideration end users coverage perspective a Cochrane outlines two potential approaches future directions. Methods: Two frameworks guide authors who are seeking include outlined. The first involves conducting full evaluations that is integrated into effects. second developing brief commentary. share set common stages but allow tailoring component skills available team. Results: number studies using methods outlined limited, further examples needed both explore these develop them. rate progress will hinge organisational leadership, capacity CCEMG, author teams other entities. Particular methodological challenges overcome relate understanding key trade-offs casual relationships decision problem informing development designed support local decision-makers. Conclusions: incorporating perspectives evidence established. Their role not provide precise estimate 'cost-effectiveness' rather help end-users determine implications components their own decisions.