Evaluation of the Melody transcatheter pulmonary valve and Ensemble delivery system for the treatment of dysfunctional right ventricle to pulmonary artery conduits

摘要: Synthetic conduits and bioprosthetic valves are used in the treatment of patients with congenital heart disease involving right ventricular outflow tract pulmonary valve. In-situ time-dependent degradation uniformly results conduit valve dysfunction. The abnormal hemodynamics imposed by dysfunction have been linked to exercise intolerance, arrhythmia, failure, sudden death. Starting childhood, affected subjected repeated open-heart surgeries restore function potentially reduce morbidity mortality. Percutaneous transcatheter replacement Melody Transcatheter Pulmonary Valve (Medtronic, Inc., Minneapolis, MN) has performed ≈8000 worldwide. implant procedure provide a far less invasive means restoring allow forego multiple operations. Recent clinical trials shown excellent durable terms function, relief obstruction, improvement functional class up 7 years from implant.