Inhibition of β-Catenin Signaling in Articular Chondrocytes Results in Articular Cartilage Destruction

作者: Mei Zhu , Mo Chen , Michael Zuscik , Qiuqian Wu , Yong‐Jun Wang

DOI: 10.1002/ART.23614

关键词:

摘要: … of articular chondrocytes was reduced, with the cartilage in … Interestingly, remaining chondrocytes were grouped into … the articular cartilage area and articular chondrocyte numbers …

参考文章(31)
Christel Cournil-Henrionnet, Didier Mainard, Patrick Netter, Pierre Gillet, Laurent Grossin, Stéphanie Etienne, Laurent Galois, Nadège Gaborit, Astrid Watrin-Pinzano, Increased apoptosis in rat osteoarthritic cartilage corresponds to degenerative chondral lesions and concomitant expression of caspase-3. Biorheology. ,vol. 43, pp. 403- 412 ,(2006)
Susumu Ohwada, Ken-ichi Tago, Shin-ichi Nagai, Yasuo Morishita, Yoji Murata, Tsutomu Nakamura, Tetsu Akiyama, Shungo Adachi, Michiru Nishita, Junko Hyodo, Hiroshi Shibuya, Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein Genes & Development. ,vol. 14, pp. 1741- 1749 ,(2000) , 10.1101/GAD.14.14.1741
Biao He, Noemi Reguart, Liang You, Julien Mazieres, Zhidong Xu, Amie Y Lee, Iwao Mikami, Frank McCormick, David M Jablons, Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations Oncogene. ,vol. 24, pp. 3054- 3058 ,(2005) , 10.1038/SJ.ONC.1208511
Liang You, Biao He, Zhidong Xu, Kazutsugu Uematsu, Julien Mazieres, Iwao Mikami, Noemi Reguart, Terry W Moody, Jan Kitajewski, Frank McCormick, David M Jablons, Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene. ,vol. 23, pp. 6170- 6174 ,(2004) , 10.1038/SJ.ONC.1207844
Masanao Tsuda, Shigeru Takahashi, Yuji Takahashi, Hiroshi Asahara, Transcriptional Co-activators CREB-binding Protein and p300 Regulate Chondrocyte-specific Gene Expression via Association with Sox9 Journal of Biological Chemistry. ,vol. 278, pp. 27224- 27229 ,(2003) , 10.1074/JBC.M303471200
J. L. Min, I. Meulenbelt, N. Riyazi, M. Kloppenburg, J. J. Houwing-Duistermaat, A. B. Seymour, H. A. Pols, C. M. van Duijn, P. E. Slagboom, Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites. Arthritis & Rheumatism. ,vol. 52, pp. 1077- 1080 ,(2005) , 10.1002/ART.20993
Timothy F. Day, Xizhi Guo, Lisa Garrett-Beal, Yingzi Yang, Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis Developmental Cell. ,vol. 8, pp. 739- 750 ,(2005) , 10.1016/J.DEVCEL.2005.03.016
Peter V.N. Bodine, Julia Billiard, Robert A. Moran, Helga Ponce-de-Leon, Sean McLarney, Annamarie Mangine, Melissa J. Scrimo, Ramesh A. Bhat, Barbara Stauffer, Jack Green, Gary S. Stein, Jane B. Lian, Barry S. Komm, The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis. Journal of Cellular Biochemistry. ,vol. 96, pp. 1212- 1230 ,(2005) , 10.1002/JCB.20599
Sang-Gu Hwang, Je-Hwang Ryu, Il-Chul Kim, Eek-Hoon Jho, Ho-Chul Jung, Kwonseop Kim, Song-Ja Kim, Jang-Soo Chun, Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms Journal of Biological Chemistry. ,vol. 279, pp. 26597- 26604 ,(2004) , 10.1074/JBC.M401401200