Transdermal drug delivery system

摘要: A transdermal drug delivery system useful for the controlled, example zero order release of one or more drugs to a selected skin area user, which comprises an impervious backing sheet and face membrane, membrane secured together form intermediate reservoir. The is macroporous has pores sufficient size avoid any rate control be transdermally delivered user. reservoir contains viscous liquid base material exude from film occlude user force hydration stratum corneum with water lower layers epidermis plurality solid microparticles generally uniformly dispersed suspended in material. containing effective therapeutic amount delivery, such as contraceptive steroid. In use exuded forms thermodynamically stable thin layer intimate contact skin, while released into