Optimal Cutoff Levels of More Sensitive Cardiac Troponin Assays for the Early Diagnosis of Myocardial Infarction in Patients With Renal Dysfunction
作者： Raphael Twerenbold , Karin Wildi , Cedric Jaeger , Maria Rubini Gimenez , Miriam Reiter
DOI: 10.1161/CIRCULATIONAHA.114.014245
关键词:
摘要: Background—It is unknown whether more sensitive cardiac troponin (cTn) assays maintain their clinical utility in patients with renal dysfunction. Moreover, their optimal cutoff levels in this vulnerable patient population have not previously been defined. Methods and Results—In this multicenter study, we examined the clinical utility of 7 more sensitive cTn assays (3 sensitive and 4 high-sensitivity cTn assays) in patients presenting with symptoms suggestive of acute myocardial infarction. Among 2813 unselected patients, 447 (16%) had renal …
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uq.edu.au参考文章(52)
Jakob L Forberg, Louise S Henriksen, Lars Edenbrandt, Ulf Ekelund, Direct hospital costs of chest pain patients attending the emergency department: a retrospective study BMC Emergency Medicine. ,vol. 6, pp. 6- 6 ,(2006) , 10.1186/1471-227X-6-6
Shanying Chen, Chunhong Huang, Bide Wu, Xuejian Lian, Xuqiao Mei, Jianxin Wan, Cardiac Troponin I in Non- Acute Coronary Syndrome Patients with Chronic Kidney Disease PLoS ONE. ,vol. 8, pp. e82752- ,(2013) , 10.1371/JOURNAL.PONE.0082752
Satoko Nakamura, Takashi Uzu, Takashi Inenaga, Genjiro Kimura, Prediction of coronary artery disease and cardiac events using electrocardiographic changes during hemodialysis. American Journal of Kidney Diseases. ,vol. 36, pp. 592- 599 ,(2000) , 10.1053/AJKD.2000.16198
Ola Hammarsten, Michael L X Fu, Runa Sigurjonsdottir, Max Petzold, Lina Said, Kerstin Landin-Wilhelmsen, Bengt Widgren, Mårten Larsson, Per Johanson, Troponin T Percentiles from a Random Population Sample, Emergency Room Patients and Patients with Myocardial Infarction Clinical Chemistry. ,vol. 58, pp. 628- 637 ,(2012) , 10.1373/CLINCHEM.2011.171496
Alma Mingels, Leo Jacobs, Etienne Michielsen, Joost Swaanenburg, Will Wodzig, Marja van Dieijen-Visser, Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays. Clinical Chemistry. ,vol. 55, pp. 101- 108 ,(2009) , 10.1373/CLINCHEM.2008.106427
, Fred S. Apple, Robert L. Jesse, L. Kristin Newby, Alan H.B. Wu, Robert H. Christenson, National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: Analytical Issues for Biochemical Markers of Acute Coronary Syndromes Circulation. ,vol. 115, ,(2007) , 10.1161/CIRCULATIONAHA.107.182881
Andrew S. Levey, Nondiabetic Kidney Disease New England Journal of Medicine. ,vol. 347, pp. 1505- 1511 ,(2002) , 10.1056/NEJMCP013462
Sylvie R. Stacy, Catalina Suarez-Cuervo, Zackary Berger, Lisa M. Wilson, Hsin-Chieh Yeh, Eric B. Bass, Erin D. Michos, Role of troponin in patients with chronic kidney disease and suspected acute coronary syndrome: a systematic review. Annals of Internal Medicine. ,vol. 161, pp. 502- 512 ,(2014) , 10.7326/M14-0746
Carmen A. Pfortmueller, Georg-Christian Funk, Grischa Marti, Alexander B. Leichtle, Georg M. Fiedler, Christoph Schwarz, Aristomenis K. Exadaktylos, Gregor Lindner, Diagnostic Performance of High-Sensitive Troponin T in Patients With Renal Insufficiency American Journal of Cardiology. ,vol. 112, pp. 1968- 1972 ,(2013) , 10.1016/J.AMJCARD.2013.08.028
Stacy EF Melanson, David A Morrow, Petr Jarolim, None, Earlier detection of myocardial injury in a preliminary evaluation using a new troponin I assay with improved sensitivity American Journal of Clinical Pathology. ,vol. 128, pp. 282- 286 ,(2007) , 10.1309/Q9W5HJTT24GQCXXX