Propofol infusion for sedation of patients with head injury in intensive care. A preliminary report.

作者: P. A. FARLING , J.R. JOHNSTON , D.L. COPPEL

DOI: 10.1111/J.1365-2044.1989.TB11228.X

关键词:

摘要: Summary Propofol was given by continuous intravenous infusion to 10 patients with severe head injuries in the intensive care unit. Heart rate, mean arterial blood pressure, intracranial cerebral perfusion pupil size and carbon dioxide tension were recorded throughout study period. A rate of 2.88 mg/kg/hour provided satisfactory sedation, recovery from propofol often rapid. Cerebral pressure significantly increased at 24 hours.

参考文章(14)
Graham Teasdale, Bryan Jennett, ASSESSMENT OF COMA AND IMPAIRED CONSCIOUSNESS: A Practical Scale The Lancet. ,vol. 304, pp. 81- 84 ,(1974) , 10.1016/S0140-6736(74)91639-0
H.K. ADAM, L.P. BRIGGS, M. BAHAR, E.J. DOUGLAS, J.W. DUNDEE, Pharmacokinetic evaluation of ICI 35 868 in man. Single induction doses with different rates of injection. BJA: British Journal of Anaesthesia. ,vol. 55, pp. 97- 103 ,(1983) , 10.1093/BJA/55.2.97
N. R. Fahmy, H. M. Alkhouli, I. Mefford, E. Caliguri, T. Durkin, HEMODYNAMICS, HISTAMINE RELEASE AND PLASMA CATECHOLAMINES FOLLOWING ANESTHETIC INDUCTION WITH DIPRIVAN OR THIOPENTAL Anesthesiology. ,vol. 65, ,(1986) , 10.1097/00000542-198609001-00357
L. H. NEWMAN, J. C. McDONALD, P. G. M. WALLACE, I. McA. LEDINGHAM, Propofol infusion for sedation in intensive care. Anaesthesia. ,vol. 42, pp. 929- 937 ,(1987) , 10.1111/J.1365-2044.1987.TB05362.X
S. A. Olczak, R. H. Greenwood, A clinical comparison of purified bovine and purified porcine insulins. Postgraduate Medical Journal. ,vol. 61, pp. 15- 18 ,(1985) , 10.1136/PGMJ.61.711.15
L. Herregods, J. Verbeke, G. Roily, F. Colardyn, Effect of propofol on elevated intracranial pressure. Preliminary results. Anaesthesia. ,vol. 43, pp. 107- 109 ,(1988) , 10.1111/J.1365-2044.1988.TB09089.X
E. MOSS, J. S. GIBSON, D. G. McDOWALL, R. M. GIBSON, Intensive management of severe head injuries. A scheme of intensive management of severe head injuries. Anaesthesia. ,vol. 38, pp. 214- 225 ,(1983) , 10.1111/J.1365-2044.1983.TB13980.X
R M Grounds, J M Lalor, J Lumley, D Royston, M Morgan, Propofol infusion for sedation in the intensive care unit: preliminary report. BMJ. ,vol. 294, pp. 397- 400 ,(1987) , 10.1136/BMJ.294.6569.397
P.H. Gast, A. Fisher, J.W. Sear, INTENSIVE CARE SEDATION NOW The Lancet. ,vol. 324, pp. 863- 864 ,(1984) , 10.1016/S0140-6736(84)90892-4
J Dundee, N J Halliday, J P Fee, Midazolam in intensive care. BMJ. ,vol. 289, pp. 1540- 1540 ,(1984) , 10.1136/BMJ.289.6457.1540-A