The forkhead transcription factors play important roles in vascular pathology and immunology.
作者： H. Yang , XF , Fang , P , Meng
DOI: 10.1007/978-1-4419-1599-3_7
关键词:
摘要: Transcription factor families are a small number of upstream master genes in “higher hierarchy” that control the expression large downstream genes. These transcription factors have been found to integrate signaling pathways underlying pathogenesis cardiovascular diseases with or without autoimmune inflammatory mechanisms. In this chapter, we organize our analysis recent progress characterization forkhead (FOX) family members vascular pathology and immune regulation into following sections: (1) Introduction FOX superfamily; (2) endothelial cell pathology; (3) smooth muscle cells; (4) factors, inflammation system. Advances these areas suggest is important regulating development diseases.
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