Gene therapy in cancer: the missing point.

摘要: Over the last century cancer research has produced data leading to a composite picture where gene mutations and epigenetic phenomena strictly relate overlap. This complexity repercussions on anti-cancer therapeutical strategies. The therapeutic pathway paved by kochian one-cause/one disease principle fails in front of multigenic multiphenomena like cancer. We still do not know what target(s) hit/modify order prevent/stop carcinogenic progression. On light statistics 2005, we discuss need exactly defining targets exploit high potential therapy.