Pulmonary thrombotic arteriopathy in patients with sickle cell disease.
作者： Moses O. Adedeji , Michael D. Hughson , Charu Subramony , Julio Cespedes , Kay Allen
DOI: 10.5858/2001-125-1436-PTAIPW
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摘要: Abstract Background.—Shortened life expectancy due to pulmonary hypertension (PH) is seen in 5% 10% of patients with sickle cell disease. The principal factors suspected causing PH are thromboemboli (PE) and situ arterial thrombosis. Objective.—To investigate the possible role that PE or thrombosis play development Methods.—Autopsies 12 disease were correlated clinical data from medical records. Results.—Right ventricular hypertrophy was present 9 patients. Six right had thrombi large elastic arteries. All artery fresh organized small muscular Hypertensive changes 5 these 6 showed no Among patients, 3 recent thrombi, as well hyp...
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