Performance of Conventional Echocardiographic Parameters and Myocardial Measurements in the Sequential Evaluation of Left Ventricular Function

摘要: Echocardiography is frequently used for sequential evaluation of left ventricular (LV) function, although the reproducibility such conventional measurements as LV ejection fraction (EF) have been questioned. The utility newer tissue Doppler imaging and atrial (LA) size in serial clinical testing are undefined. magnitude relevance changes new function were investigated compared 346 consecutive patients undergoing echocardiography. Change LA area, LVEF, E velocity (Em), transmitral to Em ratio (E/Em) over 304 ± 239 days. Changes within between parameters (after mean correction make comparable) assessed groups designated stable (n = 144) or unstable 202) according progress. A single observer remeasured these individually with paired studies side by side. Significant variability was seen all measurements, change LVEF only parameter differing (6.4 8.9% vs 9.4 5.4%; p <0.001). Tissue E/Em more variable than area LVEF. In patients, changed least most time (p <0.05). With a blinded observer, had improved (1.5 1.9 2.3 2.6 cm/s; <0.001), did visual EF. conclusion, high irrespective status. Newer no better detecting Sequential assessment should be interpreted caution, robust needed.