Ouverture régiospécifique d'un oxirane preparé á partir du d-xylose par des carbanions soufres
作者： A. Gateau-Olesker , L. Castellanos , F. Panne-Jacolot , J. Cleophax , S.D. Gero
DOI: 10.1016/S0040-4020(01)98931-8
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摘要: Abstract Two methods using the readily accessible D-xylose have been developed for synthesis of epoxides 4 and 5. The oxirane 5 was considered as a good intermediate preparation 3'-C-substituted nucleosides. crucial step 32 is regiospecific opening epoxide two carbanions, derived from either dithiane or bis(phenylthio)methane, followed by desulphurisation leading to 17. exclusive in unequivocally established 13CNMR spectroscopy.
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