Gastroscopic surveillance with targeted biopsies compared with random biopsies in CDH1 mutation carriers.
作者： Jolanda M. van Dieren , Liudmila L. Kodach , Peggy den Hartog , Lizet E. van der Kolk , Karolina Sikorska
DOI: 10.1055/A-1157-8678
关键词:
摘要: Background The International Gastric Cancer Linkage Consortium (IGCLC) consensus guideline advises prophylactic gastrectomy in early adulthood to prevent gastric cancer development CDH1 germline mutation carriers; psychosocial reasons may postpone gastrectomy. We analyzed the yield of signet-ring cell carcinoma (SRCC) during surveillance gastroscopy carriers. Methods A retrospective analysis on gastroscopies carriers was performed. The SRCC both targeted and random biopsies studied. Endoscopic (biopsy) results were compared with histopathologic outcomes specimens. Results 42 (18 men; mean age 43, range 20–82 years) underwent 96 gastroscopies. lesions identified 21 patients (50 %), by either only (n = 11), (n = 3), or (n = 7). detected 41 /377 (11 %), whereas revealed 14/1563 (0.9 %). At least one lesion found 26 30 In 18 these specimens (69 %), had been endoscopic biopsies. Missed all small superficial foci, mainly body stomach. Conclusion In our cohort carriers, an extensive protocol 69 % SRCC-positive who a resection. low number through sampling demands critical reappraisal biopsy IGCLC guideline.
thieme-connect.de参考文章(17)
Bostjan Humar, Ryuji Fukuzawa, Vanessa Blair, Anita Dunbier, Helen More, Amanda Charlton, Han Kwang Yang, Woo Ho Kim, Anthony E. Reeve, Iain Martin, Parry Guilford, Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer Cancer Research. ,vol. 67, pp. 2480- 2489 ,(2007) , 10.1158/0008-5472.CAN-06-3021
Irma Kluijt, Ester J.M. Siemerink, Margreet G.E.M. Ausems, Theo A.M. van Os, Daphne de Jong, Joana Simões-Correia, J. Han van Krieken, Marjolijn J. Ligtenberg, Joana Figueiredo, Els van Riel, Rolf H. Sijmons, John T.M. Plukker, Richard van Hillegersberg, Evelien Dekker, Carla Oliveira, Annemieke Cats, Nicoline Hoogerbrugge, , CDH1‐related hereditary diffuse gastric cancer syndrome: Clinical variations and implications for counseling International Journal of Cancer. ,vol. 131, pp. 367- 376 ,(2012) , 10.1002/IJC.26398
Anna F. Lee, Henrike Rees, David A. Owen, David G. Huntsman, Periodic acid-schiff is superior to hematoxylin and eosin for screening prophylactic gastrectomies from CDH1 mutation carriers. The American Journal of Surgical Pathology. ,vol. 34, pp. 1007- 1013 ,(2010) , 10.1097/PAS.0B013E3181E28985
Paul DP Pharoah, Parry Guilford, Carlos Caldas, International Gastric Cancer Linkage Consortium, None, Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families. Gastroenterology. ,vol. 121, pp. 1348- 1353 ,(2001) , 10.1053/GAST.2001.29611
Fátima Carneiro, David G Huntsman, Thomas C Smyrk, David A Owen, Raquel Seruca, Paul Pharoah, Carlos Caldas, Manuel Sobrinho‐Simões, None, Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. The Journal of Pathology. ,vol. 203, pp. 681- 687 ,(2004) , 10.1002/PATH.1564
Rachel S van der Post, Ingrid P Vogelaar, Fátima Carneiro, Parry Guilford, David Huntsman, Nicoline Hoogerbrugge, Carlos Caldas, Karen E Chelcun Schreiber, Richard H Hardwick, Margreet GEM Ausems, Linda Bardram, Patrick R Benusiglio, Tanya M Bisseling, Vanessa Blair, Eveline Bleiker, Alex Boussioutas, Annemieke Cats, Daniel Coit, Lynn DeGregorio, Joana Figueiredo, James M Ford, Esther Heijkoop, Rosella Hermens, Bostjan Humar, Pardeep Kaurah, Gisella Keller, Jennifer Lai, Marjolijn JL Ligtenberg, Maria O'Donovan, Carla Oliveira, Hugo Pinheiro, Krish Ragunath, Esther Rasenberg, Susan Richardson, Franco Roviello, Hans Schackert, Raquel Seruca, Amy Taylor, Anouk Ter Huurne, Marc Tischkowitz, Sheena Tjon A Joe, Benjamin Van Dijck, Nicole CT Van Grieken, Richard Van Hillegersberg, Johanna W Van Sandick, Rianne Vehof, J Han van Krieken, Rebecca C Fitzgerald, None, Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers Journal of Medical Genetics. ,vol. 52, pp. 361- 374 ,(2015) , 10.1136/JMEDGENET-2015-103094
Samantha Hansford, Pardeep Kaurah, Hector Li-Chang, Michelle Woo, Janine Senz, Hugo Pinheiro, Kasmintan A Schrader, David F Schaeffer, Karey Shumansky, George Zogopoulos, Teresa Almeida Santos, Isabel Claro, Joana Carvalho, Cydney Nielsen, Sarah Padilla, Amy Lum, Aline Talhouk, Katie Baker-Lange, Sue Richardson, Ivy Lewis, Noralane M Lindor, Erin Pennell, Andree MacMillan, Bridget Fernandez, Gisella Keller, Henry Lynch, Sohrab P Shah, Parry Guilford, Steven Gallinger, Giovanni Corso, Franco Roviello, Carlos Caldas, Carla Oliveira, Paul DP Pharoah, David G Huntsman, None, Hereditary diffuse gastric cancer syndrome: CDH1 mutations and beyond JAMA Oncology. ,vol. 1, pp. 23- 32 ,(2015) , 10.1001/JAMAONCOL.2014.168
Carol M. Park, Philip E. Reid, David C. Walker, Brian R. MacPherson, A simple, practical 'swiss roll' method of preparing tissues for paraffin or methacrylate embedding. Journal of Microscopy. ,vol. 145, pp. 115- 120 ,(1987) , 10.1111/J.1365-2818.1987.TB01321.X
Pelayo Correa, Human Gastric Carcinogenesis: A Multistep and Multifactorial Process—First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention Cancer Research. ,vol. 52, pp. 6735- 6740 ,(1992)
D Shaw, V Blair, Ann Framp, P Harawira, M McLeod, Pl Guilford, S Parry, A Charlton, I Martin, None, Chromoendoscopic surveillance in hereditary diffuse gastric cancer: an alternative to prophylactic gastrectomy? Gut. ,vol. 54, pp. 461- 468 ,(2005) , 10.1136/GUT.2004.049171